Blar i forfatter "Al-Mahdi, Rania"

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    • Comparison of antimicrobial prescribing for dental and oral infections in England and Scotland with Norway and Sweden and their relative contribution to national consumption 2010-2016 

      Smith, Andrew; Al-Mahdi, Rania; Malcolm, William; Palmer, Nikolaus; Dahlen, Gunnar; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-16)
      <p><i>Background - </i>Prescribing in dental practice has a relatively small but important contribution to the quantity of antibiotics prescribed in primary care. This study aimed to analyse antibiotic prescribing in dentistry over time (2010–2016) in 4 different Northern European countries and their relative contribution to national outpatients consumption. <p><i>Methods - </i>This retrospective ...

    • Comparison of antimicrobial prescribing for dental and oral infections in England and Scotland with Norway and Sweden and their relative contribution to national consumption 2010–2016 

      Smith, Andrew; Al-Mahdi, Rania; Malcolm, William; Palmer, Nikolaus; Dahlén, Gunnar; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-16)
      <i>Background</i> - Prescribing in dental practice has a relatively small but important contribution to the quantity of antibiotics prescribed in primary care. This study aimed to analyse antibiotic prescribing in dentistry over time (2010–2016) in 4 different Northern European countries and their relative contribution to national outpatients consumption.<p><p> <i>Methods</i> - This retrospective ...

    • Identification of novel roles and new modes of regulation for the atypical MAP kinases ERK3 and ERK4 

      Al-Mahdi, Rania (Doctoral thesis; Doktorgradsavhandling, 2015-11-13)
      The atypical MAP kinases ERK3 and ERK4 are the main characters in this study. ERK3 and ERK4 were for long considered as orphan proteins without known upstream activators. However, in 2011 two studies had detected that group I p-21 protein activated kinase (PAKs) can constitutively phosphorylate ERK3 and ERK4 in their activation loop. The only well-characterized substrate for ERK3 and ERK4 at that ...

    • A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression 

      Diab, Joseph; Al-Mahdi, Rania; Gouveia, Sandra; Hansen, Terkel; Jensen, Einar; Goll, Rasmus; Moritz, Thomas; Florholmen, Jon; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-22)
      <p><i>Background</i> - The bioactive metabolites of omega 3 and omega 6 polyunsaturated fatty acids (ω-3 and ω-6) are known as oxylipins and endocannabinoids (eCBs). These lipid metabolites are involved in prompting and resolving the inflammatory response that leads to the onset of inflammatory bowel disease (IBD). This study aims to quantify these bioactive lipids in the colonic mucosa and to ...

    • Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2 

      Perander, Maria; Al-Mahdi, Rania; Jensen, Thomas Clemens; Nunn, Jennifer Ann Lillebo; Kildalsen, Hanne; Johansen, Bjarne Herold; Gabrielsen, Mads; Keyse, Stephen M; Seternes, Ole Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-02)
      The atypical MAP kinases ERK3 and ERK4 are activated by phosphorylation of a serine residue lying within the activation loop signature sequence S-E-G. However, the regulation of ERK3 and ERK4 phosphorylation and activity is poorly understood. Here we report that the inducible nuclear dual-specificity MAP kinase phosphatase (MKP) DUSP2, a known regulator of the ERK and p38 MAPKs, is unique amongst ...

    • Restorative treatment decisions for carious lesions: Do Russian dentists and dental students apply minimal intervention dentistry? 

      Drachev, Sergei Nikolaevich; Galieva, Alexandra S.; Yushmanova, TN; Polivanaya, Elena A.; Stangvaltaite-Mouhat, Lina; Al-Mahdi, Rania; Leinonen, Jukka; Stein, Linda Maria; Davidova, Nadezhda G.; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-15)
      Background - The concept of minimal intervention dentistry (MID) includes both delayed restorative treatment and conservative caries removal, and is now recognised as an evidence-based approach for dental caries management. In order to determine if dental professionals in Russia are incorporating this concept into their clinical practice, we investigated the restorative treatment decisions of Russian ...

    • Restorative treatment decisions for carious lesions: Do Russian dentists and dental students apply minimal intervention dentistry? 

      Drachev, Sergei Nikolaevich; Galieva, Alexandra S.; Yushmanova, Tatiana N.; Polivanaya, Elena A.; Stangvaltaite-Mouhat, Lina; Al-Mahdi, Rania; Leinonen, Jukka; Stein, Linda; Davidova, Nadezhda G.; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-15)
      <p><b>Background</b> The concept of minimal intervention dentistry (MID) includes both delayed restorative treatment and conservative caries removal, and is now recognised as an evidence-based approach for dental caries management. In order to determine if dental professionals in Russia are incorporating this concept into their clinical practice, we investigated the restorative treatment decisions ...